Road Reimagined Synapse Synapse Synapse
Winning Road Bike of the Year didn’t just turn heads, it proved that Synapse is built for how people really ride. With race-bred performance and real-world capability, Synapse delivers speed, efficiency, and confidence on the roads you actually use. Its lightweight, aero-tuned carbon frame, generous tire clearance, and tuned compliance make long days, rough pavement, and fast group rides feel effortless. Add award-winning SmartSense and integrated StashPort storage, and Synapse becomes the one road bike that truly makes sense for most riders.
"Synapse represents the new template for a non-racing road bike. It has handling that’s swift and stable, and gives confidence in spades. It's compliant but doesn’t lose the excitement that comes from a stiff bike, plus it features the best application of the SmartSense system to date."
-Bike Radar 2025 Bike of the Year
"Cannondale have brought one of the most versatile bikes, and quite possibly the best all-road option, onto the market. It’s not just the balanced handling and sporty ride that impress. The hard facts like tire clearance, rider ergonomics and aero optimisation all come together to make the Synapse the only bike you really need in your garage."
- Gran Fondo
"The Synapse forgoes comfort gimmicks in favor of ample tire clearance, solid geometry, and clean integration to deliver an exceptional riding experience. It sets a new standard for endurance road bikes."
- Bicycling
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Synapse | Road Reimagined
Road Reimagined
Paved, Unpaved, Unbothered.
Synapse Carbon clears measured 42 mm tires and comes standard with 30–32 mm rubber on wide rims. That extra volume delivers more grip, comfort, speed, and protection when the road turns rough. Call it endurance, all-road, or gravel-lite. We call it Synapse—the only mate you need.
Far Meets Fast
The comfort and compliance to go far, and the stiffness and aerodynamics to get there faster. Much like Lachy’s far, fast Aussie ride, Synapse is engineered to go long and smooth, at a WorldTour-level pace.
Performance, Guaranteed
We sent Synapse to hell and back to get it ride-ready for you. Developed in partnership with our pro-riders, it was used, abused and and refined until it met their exacting standards, and ours. Built on our decades of experience, and backed by our lifetime warranty, it's sure to meet yours as well.
Confidence Built In
Ride confident with 2nd-gen SmartSense on Synapse. Fully integrated and powered by a single downtube battery, it features intelligent lights and rear-facing radar controlled via the Cannondale app. Recognized by TIME as one of The Best Innovations of 2025 and the Design & Innovation Award.
The Only Mate You Need
