SuperSix EVO meets Synapse
Cannondale SuperSix EVO or Synapse: Which Road Bike Is Right for You?
When it comes to choosing the perfect performance road bike, the conversation often starts with two icons in the Cannondale lineup: the SuperSix EVO and the Synapse. Both deliver incredible speed, precision engineering, and Cannondale’s signature ride feel, but they serve different styles of riders and different types of rides. Watch the video below and find out which road bike is the perfect fit for you.
Synapse meets SuperSix
So, it’s no surprise that the SuperSix EVO is the weapon of choice for our pros at EF Pro Cycling.
With clearance for up to 42mm tires, Synapse is one bike with multiple personalities. Stick with 30-34mm tires for a racy, responsive road feel, or swap to larger 40-42mm tires for extra comfort and grip on rough roads or light gravel. Its versatility and convenience are further enhanced with the StashPort downtube storage and, on select models, our SmartSense system of integrated lights and radar.
This combination makes Synapse ideal for long adventures, Gran Fondo racing, solo efforts, or group rides. Perfect for riders who want one bike that can handle almost anything.
Do you need proof that Synapse is indeed a performance bike? Lachlan Morton used Synapse to set the record for the fastest known ride around Australia, choosing its unique blend of comfort, clearance, and performance for this ultra‑long‑distance challenge.
Geometry That Matches Your Riding Style
The biggest difference between the two platforms comes down to fit and handling:
- Aggressive Cannondale road fit
- Lowest stack height
- Snappy, race-focused handling
- Fast above all. Built to get to the line first
- ~25 mm taller stack than SuperSix EVO Gen. 5 for a more relaxed position
- Slightly longer wheelbase
- Increased trail measurement for added stability and confident handling
- Still sporty and fun, just more accessible and all-day-friendly
The result: SuperSix EVO = pure race. Synapse = high-performance + all-around versatility.
Which One Should You Choose?
Your choice comes down to how you balance performance and versatility:
Choose SuperSix EVO if:
- Speed, aerodynamics, and razor-sharp handling are your top priorities
- You prefer an aggressive race fit
- You want a lightweight, stripped-down machine designed to go fast
Choose Synapse if:
- You want high performance plus everyday convenience
- You prefer a more upright, endurance-focused fit
- You value tire clearance, versatility, and long-ride comfort
Both bikes carry Cannondale’s performance heritage. The difference is how—and where—you want to ride.