SuperSix EVO meets Synapse

Cannondale SuperSix EVO or Synapse: Which Road Bike Is Right for You?

When it comes to choosing the perfect performance road bike, the conversation often starts with two icons in the Cannondale lineup: the SuperSix EVO and the Synapse. Both deliver incredible speed, precision engineering, and Cannondale’s signature ride feel, but they serve different styles of riders and different types of rides. Watch the video below and find out which road bike is the perfect fit for you.

Synapse meets SuperSix

PLAY FILM
SuperSix EVO: Pure Racing Performance
The SuperSix EVO is built for one thing: going fast. It’s a stripped‑down, ultra‑efficient race machine created for riders who prioritize outright speed and podium‑level performance above all else. With its aggressive geometry, low stack height, and aerodynamic design, SuperSix EVO gives you the responsiveness and precision needed to push the pace, attack climbs, and sprint for the line.

So, it’s no surprise that the SuperSix EVO is the weapon of choice for our pros at EF Pro Cycling.
Synapse: High-Performance Meets Real‑World Usability
The Synapse delivers a similar level of performance, but adds everyday versatility, comfort, and smart features. Designed for riders who want speed and convenience, Synapse brings together Cannondale’s aero expertise, engineering DNA, and endurance‑tuned geometry.

With clearance for up to 42mm tires, Synapse is one bike with multiple personalities. Stick with 30-34mm tires for a racy, responsive road feel, or swap to larger 40-42mm tires for extra comfort and grip on rough roads or light gravel. Its versatility and convenience are further enhanced with the StashPort downtube storage and, on select models, our SmartSense system of integrated lights and radar.

This combination makes Synapse ideal for long adventures, Gran Fondo racing, solo efforts, or group rides. Perfect for riders who want one bike that can handle almost anything.

Do you need proof that Synapse is indeed a performance bike? Lachlan Morton used Synapse to set the record for the fastest known ride around Australia, choosing its unique blend of comfort, clearance, and performance for this ultra‑long‑distance challenge.

Geometry That Matches Your Riding Style

The biggest difference between the two platforms comes down to fit and handling:

SuperSix EVO Geometry

  • Aggressive Cannondale road fit

  • Lowest stack height

  • Snappy, race-focused handling

  • Fast above all. Built to get to the line first

Synapse Geometry

  • ~25 mm taller stack than SuperSix EVO Gen. 5 for a more relaxed position

  • Slightly longer wheelbase

  • Increased trail measurement for added stability and confident handling

  • Still sporty and fun, just more accessible and all-day-friendly

The result: SuperSix EVO = pure race. Synapse = high-performance + all-around versatility.

Which One Should You Choose?

Your choice comes down to how you balance performance and versatility:

Choose SuperSix EVO if:

Choose Synapse if:

Both bikes carry Cannondale’s performance heritage. The difference is how—and where—you want to ride.

Compare Products

Add another product to compare
Specifications

Details

Platform

Details

      Model Name

      Details

          Model Code

          Details

              Frameset

              Frame

              Details

                  Headset

                  Details

                      Rear Shock

                      Details

                          E-System

                          Drive Unit

                          Details

                              Battery

                              Details

                                  Charger

                                  Details

                                      Display

                                      Details

                                          Certifications

                                          Details

                                              Drivetrain

                                              Rear Derailleur

                                              Details

                                                  Front Derailleur

                                                  Details

                                                      Shifters

                                                      Details

                                                          Chain

                                                          Details

                                                              Crank

                                                              Details

                                                                  Rear Cogs

                                                                  Details

                                                                      Bottom Bracket

                                                                      Details

                                                                          Pedals

                                                                          Details

                                                                              Brakes

                                                                              Brakes

                                                                              Details

                                                                                  Brake Levers

                                                                                  Details

                                                                                      Wheels

                                                                                      Front Hub

                                                                                      Details

                                                                                          Rear Hub

                                                                                          Details

                                                                                              Rim Material

                                                                                              Details

                                                                                                  Rim Depth

                                                                                                  Details

                                                                                                      Rim Outer Width

                                                                                                      Details

                                                                                                          Rim Inner Width

                                                                                                          Details

                                                                                                              Rim Type

                                                                                                              Details

                                                                                                                  Nipple Type

                                                                                                                  Details

                                                                                                                      Wheel Weight

                                                                                                                      Details

                                                                                                                          Dish Offset

                                                                                                                          Details

                                                                                                                              Effective Rim Diameter

                                                                                                                              Details

                                                                                                                                  Maximum Spoke Tension

                                                                                                                                  Details

                                                                                                                                      Max Tire Pressure

                                                                                                                                      Details

                                                                                                                                          Brake Type

                                                                                                                                          Details

                                                                                                                                              Rider Weight Limit

                                                                                                                                              Details

                                                                                                                                                  Spokes

                                                                                                                                                  Details

                                                                                                                                                      Spoke Count

                                                                                                                                                      Details

                                                                                                                                                          Spoke Length (NDS-DS)

                                                                                                                                                          Details

                                                                                                                                                              Spoke Type

                                                                                                                                                              Details

                                                                                                                                                                  Tire Size

                                                                                                                                                                  Details

                                                                                                                                                                      Wheel Size

                                                                                                                                                                      Details

                                                                                                                                                                          Tires

                                                                                                                                                                          Details

                                                                                                                                                                              Front Tire

                                                                                                                                                                              Details

                                                                                                                                                                                  Rear Tire

                                                                                                                                                                                  Details

                                                                                                                                                                                      Tire Bead

                                                                                                                                                                                      Details

                                                                                                                                                                                          Tire Casing

                                                                                                                                                                                          Details

                                                                                                                                                                                              Tire Protection

                                                                                                                                                                                              Details

                                                                                                                                                                                                  Tire Type

                                                                                                                                                                                                  Details

                                                                                                                                                                                                      Components

                                                                                                                                                                                                      Handlebar

                                                                                                                                                                                                      Details

                                                                                                                                                                                                          Grips

                                                                                                                                                                                                          Details

                                                                                                                                                                                                              Saddle

                                                                                                                                                                                                              Details

                                                                                                                                                                                                                  Seatpost

                                                                                                                                                                                                                  Details

                                                                                                                                                                                                                      Connectivity

                                                                                                                                                                                                                      Components

                                                                                                                                                                                                                      Details

                                                                                                                                                                                                                          Power Meter

                                                                                                                                                                                                                          Details

                                                                                                                                                                                                                              Speed Sensor

                                                                                                                                                                                                                              Details

                                                                                                                                                                                                                                  Extra

                                                                                                                                                                                                                                  Extra 1

                                                                                                                                                                                                                                  Details

                                                                                                                                                                                                                                      Visibility

                                                                                                                                                                                                                                      Lights

                                                                                                                                                                                                                                      Details

                                                                                                                                                                                                                                          Paint

                                                                                                                                                                                                                                          Details

                                                                                                                                                                                                                                              Tire Sidewalls

                                                                                                                                                                                                                                              Details